SKINVIVE™ is an injectable hyaluronic acid used for improving skin quality attributes such as hydration and elasticity. SKINVIVE™ hydrates‖ and refreshes¶ from within1,2,3,** for radiant,†† smooth‡‡ and healthy-looking* skin.1
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Footnotes
† Skin hydration was measured using the MoistureMeterD instrument with the XS 5 and S 15 probes (depth of effective measurement: 0.5 and 1.5 mm, respectively).2
‡ Long lasting is up to 9 months following a single treatment.2
§ Instrument measures of skin hydration, smoothness, and skin deformation parameters were performed on the cheek, forehead, and neck of one side of the face on Day 0 and at 30 days after initial treatment (before touch up), Months 1, 4, 6, and 9 after the last treatment, and Month 1R. Skin hydration was measured using the MoistureMeterD instrument (n=131) and top-up treatment administered at Day 30 (n=31).2
‖‖ Based on a search of published clinical studies of injectable HA treatments in March 2023. A duration of 9 months was established with SKINVIVE™.4
¶ Lasting up to 9 months as reported by 51.2% of patients. As reported by 127 of 131 patients (2 subjects did not respond) in a composite satisfaction score, which includes how refreshed their facial skin looked.1
** Data derived from a prospective, non-randomised, interventional, open-label study where 11 healthy patients (men [n=2] and women [n=9]) received intradermal VYC-12L treatment on the volar forearm. Clinical probes assessed skin quality at baseline and Months 1 and 3 post-treatment. Punch biopsies were collected at Months 1 and 3 posttreatment to evaluate histologic and genomic changes.3
†† Lasting up to 9 months as reported by 63% of patients. As reported by 127 of 131 patients in a composite satisfaction score, which includes how radiant their facial skin looked.1
‡‡ Lasting up to 9 months as reported by 55.1% of patients. As reported by 127 of 131 patients in a composite satisfaction score, which includes how smooth their facial skin looked.1
* Lasting up to 9 months as reported by 76.2% of patients. As reported by 127 of 131 patients (1 subject did not respond) in a composite satisfaction score, which includes how healthy their skin looked.1
References
1. Ogilvie P et al. J Cosmet Dermatol. 2020;19(5):1065–1070.
2. Niforos F et al. Clin Cosmet Investig Dermatol. 2019;12:791–798.
3. Safa M et al. Clin Cosmet Investig Dermatol. 2022;15:411–426.
4. Allergan Aesthetics. Unpublished data. SKINVIVE™ by JUVÉDERM® – 9-month duration of skin hydration in clinical trials. March 2023.
Please consult a registered medical practitioner for treatment plan.
